Nicotinamide adenine dinucleotide (NAD) is one of the most essential molecules in your body. In fact, you’ll find it in every single cell working in more chemical reactions than any other vitamin-derived molecule. When the molecule has oxidized and becomes inactive, it is known as NADH, but in its active form, it is known as NAD+. NAD+ is a coenzyme of Niacin (Vitamin B3) which acts as a helper molecule that binds to a protein in order to activate an Enzyme reaction. Enzymes are responsible for 1000's of different biochemical reactions throughout the body.


As we age, NAD+ levels naturally decrease within our body. Habits such as overeating and excessive alcohol consumption can also lead to a decline in NAD+. Unfortunately, low levels of NAD+ have been linked to health issues like premature skin aging, Alzheimer’s disease, diabetes, heart disease, and vision loss.

NAD+ IV therapy is a treatment that seeks to replenish the levels of this vital molecule in your body with a solution administered through an IV.


  • Maximize brain function- Cognitive decline is one of the most common effects of aging. Neurodegeneration, or the loss of neuron function and structure, causes our mind to work slower and our memories to become fuzzy. NAD+ IV serves as a brain restoration that increases neuron function, protects cells from toxins and damage, and promotes the process of mitochondrial biogenesis. This translates to increased mental clarity, improved concentration, sharpened memory, and a healthy mood boost.

  • Cell regeneration- Increasing the levels of NAD+ throughout your body allows it to better heal itself from injury. Research shows that ATP and NAD+ may alert the body’s natural immune response when the cell is under stress or where inflammation is present. In addition to this, NAD+ is crucial to the activation of poly ADP-ribose polymerases (PARPs), which repair damaged DNA.

  • Beat fatigue- Chronic fatigue can be a debilitating condition, and experts aren’t exactly clear on the root cause of the problem. Oftentimes, doctors prescribe a combination of sleep medication and antidepressants, which may not actually improve chronic fatigue. IV NAD+ therapy works by supplying energy that is needed on the cellular level in order to heal.

  • Slow Aging- Enzymes known as "sirtuins", play a major role in the body’s aging process through DNA protection and inflammation regulation. Sirtuins are dependent on NAD+ to stop and start the protective pathways that have links to the pathologies of age-related diseases. This means that sirtuins and NAD+ are able to turn certain genes off, almost like a light switch, that promote aging, fat storage, and blood sugar management issues.



All individuals, healthy or otherwise, can benefit from oral dosing of NAD+ precursors such as Nicotinamide Riboside. Oral supplements of NAD+ itself are ineffective at raising levels in the body due to malabsorption unless they are lyposomal versions.


With that being said, NAD+ therapy has benefits for everyone. As you read in the list above, it can be a helpful treatment for those feeling sluggish or always seem to be trapped in a fog. People experiencing low energy and slow metabolism are excellent candidates for therapy. But NAD+ can also be used by those looking for overall performance enhancing benefits in athletic training and exercise. Research has shown that intense exercises decrease NAD+ levels, but when that level is replenished, individuals experienced better performance and greater endurance.

Those who suffer from chronic conditions may also find relief and the lessening of symptoms with NAD+ therapy. Conditions that may benefit from the therapy include:

  • Improving Physical Performance in Athletic's

  • Mitochondrial dysfunction

  • Chronic fatigue

  • Substance Abuse/ Addiction 

  • Depression/ Anxiety

  • Chronic Pain/ Fibromyalgia

  • Sleep Disorders

  • Brain Injuries 

  • Autism

  • Lyme Disease

  • Neurodegeneration/Alzheimer’s disease

  • Parkinson’s disease

  • Multiple sclerosis




We provide weekly NAD+ infusions as an aide to slow down the aging process and restore energy and well being.

  • NAD+ fights aging  by restoring youthful function of basic life sustaining processes in every single cell.

  • NAD+ is described as a major advance in “systemic anti-aging medicine”

  • NAD is necessary for cellular regeneration.

  • NAD+ turns off genes that are responsible for aging.- silences genes for proteins that accelerate aging (through Sirtuins).

  • NAD+ has an important role in DNA repair and telomere maintenance

  • Protection of brain cells and is described as a novel neurotransmitter.

  • Important cell signaling function.

  • Turns on enzymes (Sirtuins) that slows aging.

  • Restores mitochondrial decay and dysfunction.

  • Mitigates oxidative stress.

  • Anti inflammatory - Activates enzymes to prevent and correct DNA damage.

How does NAD+ IV therapy work for addiction?

Basically, using drugs and alcohol will deplete the body’s natural stores of NAD. Because of this, the brain doesn’t receive the same energy it normally would get from breaking down food. Research is being conducted on NAD+ IV as a form of addiction therapy, and studies are showing promising results. NAD+ Therapy floods the brain with NAD to replenish its stores. This process can also flush out all of the drugs that are still in your system, minimizing withdrawal symptoms and reduces the cravings for alcohol and opioids. This in turn, makes recovery much easier physically and mentally, so you’ll feel better quicker. It is recommended that you get NAD+ booster infusions every couple of months to keep your levels normal.

The therapy is not a cure for any form of addiction, but it can aid in healing the brain on the cellular level, giving individuals a better chance at long term recovery. 

What are the side effects of taking NAD+?

Due to extra ATP, which is fuel for your cells throughout your body, NAD+ treatments must be infused over 2 hours minimum. If the infusion is going too fast for your body to tolerate it can cause an increase in physiological activity including but not limited to: nasal congestion, stomach cramping, tingling in your arms, lightheadedness, nausea, sweating and even heaviness in your chest. Symptoms can be instantly stopped by slowing the rate of infusion. 



NAD+ therapies should be custom tailored to the patient’s specific needs!  

The most successful and therapeutic way to increase NAD+ levels is through intravenous injection. An individual’s type and severity of condition greatly determines the dosage, frequency, and duration of treatment when it comes to NAD+ Intravenous Therapy.  


Some patients may benefit from a monthly injection, where as others will benefit from much more intensive treatment plans. Often for conditions such as addiction or chronic illness intensive slow drip IV sessions over the course of several days is recommended to achieve more dramatic and lasting results. 

*Optimal NAD+ treatment protocol requires 4 consecutive days*

 to maximize results 8-10 treatments recommended 


Intravenous NAD Therapy can have some really remarkable effects on energy, cognitive performance, mental health, and overall health. After an NAD Therapy session patients often report feeling increased energy, mental clarity, and focus. As well as an enhanced sense of purpose, improved mood, and lower levels of pain. This special molecule is truly revolutionizing the way we address healing and aging in today’s world.

Prices range between $150-$1000 depending on what therapy is being performed. Different therapies can be coupled together to achieve maximum healing. 




First time receiving NAD+ therapy? This introductory dose of NAD+ will be your first treatment here at The Earth is Calling Natural Remedies. Through a smaller dose administered via IV injection, we can gently introduce your body to the profound effects of NAD+ therapy.

Although we naturally produce NAD+ it, like most things, it reduces with age. This “miracle” molecule is mostly regarded for its effect on aging and is considered the closest we’ve gotten to the fountain of youth. Intravenous use of NAD+ activates enzymes in the bloodstream called “sirtuins” which promotes the “good” aspects of your genes which facilitates one to stay healthier for longer, reducing the side effects of aging.

NAD+ Treatment Protocol:


For 1st time patients: 2 hour infusion of 250mg NAD+ Fountain of Youth Infusion




Experience the life-changing effects of NAD+ infusions. This full dosage NAD+ infusion is administered via IV, for best results add our Brain Boost Vitamin IV.

With intravenous NAD+ therapy, the molecule works rapidly to repair cells throughout the body and neurons in the brain. It serves as a catalyst in ultimate brain renovation, allowing us to mentally reach higher than ever before and helps overcome depression, anxiety and common mood disorders. With optimal brain function, you can make everyday a good day.

NAD+ Treatment Protocol:


4 hour infusion of 500mg NAD+ Brain Boost


$2,920 (Save:$300)
Treatment of NAD+ 500mg drip x 3 days, 750mg drip X 1 day and 1000mg drip X 1 day

NAD+ has been linked to brain renovation and drastically reduces drug dependence by rejuvenating the opiate receptors. Restoration of proper brain biochemistry helps to break addiction. Replenish brain nutrients that have been depleted by substance abuse.

NAD+ Treatment Protocol:
2 hour infusion of 250mg X 1 day
3 hour infusion of 500mg x 2 days
4 hour infusion of 750mg
6 hour infusion of 1000mg NAD
**Treatment plans can be modified and tailored to suit your individual needs**
NAD+ Price Breakdown
50-100mg: $250 
101-250mg: $375
500mg: $550 
750mg: $725 
1,000mg: $875 


1 Chance, Britton, et al. “Intracellular Oxidation-Reduction States in Vivo The microfluorometry of pyridine nucleotide gives a continuous measurement of the oxidation state.” Science 137.3529 (1962): 499-508.

2 Imai, Shin-ichiro, and Leonard Guarente. “NAD+ and sirtuins in aging and disease.” Trends in cell biology 24.8 (2014): 464-471.

3 Mach, John, et al. “The Effect of Antioxidant Supplementation on Fatigue during Exercise: Potential Role for NAD+ (H).” Nutrients 2.3 (2010): 319-329.

4 Shetty, Pavan K., Francesca Galeffi, and Dennis A. Turner. “Nicotinamide pre-treatment ameliorates NAD (H) hyperoxidation and improves neuronal function after severe hypoxia.” Neurobiology of disease 62 (2014): 469-478.

5 Verdin, Eric. “NAD+ in aging, metabolism, and neurodegeneration.” Science 350.6265 (2015): 1208-1213.

6 Cederbaum, Arthur I. “Alcohol metabolism.” Clinics in liver disease 16.4 (2012): 667-685.

*Disclaimer: Individual patient results may vary based on a patient’s medical history and other factors and these results should not be expected or anticipated. We do not claim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. Information on this site is not intended to replace the advice of your physician or healthcare provider. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or having medical condition. Statements made about products, therapies or services have not been evaluated by the Food and Drug Administration.*