CGF-PRP Injection Therapy

What is CGF-PRP and where do you get it?

We all have platelets in our blood. CGF-PRP stands for “Concentrated growth factor platelet rich plasma.” 

CGF-PRP is the next generation in PRP therapy!! It is a popular process among celebrities due to its regenerative applications in the pain & beauty industries. It contains significantly more of “the good stuff” including Transforming growth factors beta (TGFB), Platelet derived growth factors (PDGF)-containing exosomes and CD34+ stem cells, Insulin-like growth factors (IGF), Vascular endothelial growth factors (VEGF), Epithelial growth factors (EGF), and Fibroblast growth factors-2 (FGF-2) than PRP derived from traditional methods. 


Extracting CGF-PRP from your blood requires a specialized technique using a state-of-the-art centrifuge that spins the blood using a specific, research-driven protocol.

The CGF-PRP is injected with a small needle in regions of the body that can stimulate the production of new cells, repair damaged cells, and extend the life of existing cells to regenerate the locally treated tissue.

Platelet rich plasma is not only rich in platelet cells but also numerous growth factors that play a role in tissue growth, healing, and regeneration.

Why should you consider it? 


Conventional medical therapies can help maintain reasonable skin and tissue health, but often times lack in their regenerative benefits.  By combining PRP therapy with existing modern medical and natural therapies we can help you optimize cellular health and further prevent age related decline.  


 Stem cell therapy can be used to augment or replace the PRP if desired.  We use the highest quality mesenchymal stem cells available in Colorado from a company that has done extensive screening, testing and consent to isolate these from birth tissue.

What is microneedling?

During a microneedling session, Nurse Holly will gently create tiny openings in the surface of the skin using THE SKIN PEN microneedling device. The SKIN PEN is the first microneedling device in the world cleared by the FDA. These openings, called “fractionated injuries,”  stimulate the creation of collagen and also create a point of entry for the application of CGF-PRP/stem cells or other topical serums that refresh the skin.

Microneedling can be used to enhance the appearance of virtually any section of the body, including:

  • Face

  • Neck and neckline

  • Chest

  • Back

  • Stomach

  • Arms and legs

  • Hands

Is microneedling right for me?


Microneedling can begin relieving a broad range of skin conditions almost immediately. The treatment is effective on:

  • Uneven skin tone

  • Sagging skin

  • Wrinkles

  • Acne and other scars

  • Large pores

  • Stretch marks

An average visit involving microneedling takes about 1 hour. Areas of severely damaged skin might require more than one appointment before results become apparent.


 PRP is considered safe for most people, it is not recommended for anyone who has the following medical conditions: 


-Hepatitis C


-Any type of blood cancer

-Cardiovascular disease, which requires taking a blood thinner

-Skin cancer in the area to be treated

Other things to consider:

-Use or recently used Acutane for acne

-Still have active acne resulting in new scarring

-Scar easily 

-Have a history of poor wound healing

-Have undergone skin radiation in the last 12 months

Where can you inject the CGF-PRP and/or Stem cells to help me look and function better?

You Can Diminish the Signs of Aging!!


CGF-PRP Ozone Facial OR Stem Cell Facial

The facial region is comprehensively assessed with the patient. CGF-PRP is collected and  numbing cream is applied to the face for 15 minutes or longer. CGF-PRP is applied to the face and the SKIN PEN micro-needling device is used to make hundreds of small holes in the epidermis/dermis which will further stimulate and allow the CGF-PRP growth factors to penetrate deep into skin. Wrinkles and other regions of the face may be injected with a very small needle.

Clients receiving ozone treatments are less likely to experience post-injection pain and are more likely to recover faster when compared to patients receiving PRP treatment alone.


Stem cells can be used with CGF-PRP or substituted entirely. Benefits include a more youthful appearance of the face from increased collagen/elastin production, improved volume and improved circulation to the skin. 


When you want to rejuvenate your skin but you don’t want to undergo surgery, a Placental-derived tissue facial may be the perfect solution. Placental-derived tissue facials naturally diminish the signs of aging, strengthen your skin, and restore a bright, youthful appearance.
How do Placental-Derived Tissue Transplants rejuvenate my skin?

Placental-derived tissue cells (STEM CELLS) have the exceptional ability to self-replicate and produce the many different cells needed to replace old skin, repair damaged skin, and restore healthy skin. They also release proteins called growth factors, which accelerate healing, stimulate

new blood vessel growth, and promote healthy cells and tissues.

When nurse Holly introduces Placental-derived tissue cells into your skin, they boost collagen and elastin

 The Earth is Calling Natural Remedies utilizes a bio-ethically obtained topical placental-derived tissue product, specifically designed to maximize skin regeneration. MSC's, extracellular matrix, placental MSC-derived acellular and powerful growth factors penetrate deep into the outer layer of skin, which is the most damaged and receives the least amount of nutrients on a daily basis. 


Scalp Regions of mild to moderate thinning can be treated with CGF-PRP OR stem cells,  under skin, and on top of skin.  The area is prepped, and numbing cream applied.  A small amount of lidocaine may also be injected.  The CGF-PRP or stem cells are injected under the regions of hair thinning followed by use of topical CGF-PRP.  Prior to placing the CGF-PRP on top of skin, the SKIN PEN micro-needling device is used to make hundreds of small holes in the epidermis/dermis which will further stimulate and allow the CGF-PRP growth factors penetrate deep into the scalp stimulating hair follicles. The process is meticulous — with injections beginning across the scalp, approximately at every half inch over the area of thinning hair — but typically, the entire procedure takes about an hour..


Stem cells or Exosomes can be used with CGF-PRP or substituted entirely. Exosomes are super tiny, nano-sized vesicles that contain proteins, microRNA's and lipids. They help cells communicate and can be mixed with PRP to illicit a more immediate therapeutic response! We utilize a purified Exosome product derived from placental MSC's.


PRP therapy uses injections of a concentration of a patient’s own platelets to accelerate the healing of injured tendons, ligaments, muscles and joints. In this way, PRP injections use each individual patient's own healing system to improve musculoskeletal problems. This therapy is amazing for anyone suffering from chronic pain.


Nurse Holly provides a range of services that complement your stem cell or CGF-PRP Ozone facial, such as:

  • Micro frequency skin therapy wand

  • Fountain of Youth IV infusion (ADD: NAD+ for the ultimate anti-aging experience!)

  • Stem cell regenerative cream with peptides

These additional services further improve the appearance of your skin and maintain the results of your facial by hydrating, restoring firmness, reducing fine lines and wrinkles, and diminishing hyperpigmentation.

Additionally, the micro frequency therapy repairs skin by boosting energy (ATP) in skin cells, improving circulation, and reducing inflammation.

If you’re ready to brighten your skin and fight the signs of aging naturally, call The Earth is Calling Natural Remedies and schedule your appointment today!!

Treatment Recommendations, Recovery and Results

For optimal results, we recommend a series of 4 to 6 treatments. Each treatment must be spaced a minimum of one month apart. Once the desired results have been achieved, it is best to have maintenance treatments 2 to 4 times per year. Collagen takes 21 days to regrow, results are usually seen within 8 weeks. Results are permanent because the body is rejuvenating itself. However, as the skin continues to age and is exposed to environmental stressors, follow up treatments are recommended. 

Microneedling is non-surgical and minimally invasive, so it has a mild recovery. Here is a general timeline of what you can expect before and after your procedure:

  • 24 hours before treatment: Stop your normal skincare routine. Don't apply any exfoliating agents.

  • 6-8 hours after treatment: Don't apply anything to the treated area, including makeup or sunscreen. Avoid wearing clothing, headbands, or scarves over the treated area, as well. You'll experience redness and swelling that will resolve in a few days.

  • 1-3 days after treatment: Wash treated skin with a sensitive skin cleanser. Apply a hyaluronic acid serum and put on a natural facial sunscreen before going outside. Avoid anything that will make you sweat, including hot tubs, saunas, and exercise. Don't wear makeup.

  • 4 days after treatment: You may resume your normal skin-care, makeup, and exercise routines. Continue to wear facial sunscreen when going outside.

*Disclaimer: Individual patient results may vary based on a patient’s medical history and other factors and these results should not be expected or anticipated. We do not claim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. Information on this site is not intended to replace the advice of your physician or healthcare provider. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or having medical condition. Statements made about products, therapies or services have not been evaluated by the Food and Drug Administration.*